Brief Notes on Kawasaki Disease 2001.3.24

Brief Notes on Kawasaki Disease 2001.3.24

This disease is commonly seen in children, presenting with high fever, rash, lymphadenopathy, conjunctival, lingual, and oral mucosal redness and swelling. Pathologically, it is considered a lymph node–skin–mucosa syndrome. The primary pathological change is vasculitis, affecting arteries, veins, and capillaries, though capillaries are most frequently involved. Because inflammation affects the skin, mucosa, and lymph nodes, these areas become swollen, red, hot, and painful. When large vessels are affected, the increased pressure and inflammatory damage reduce the elasticity of the vessel walls, leading to dilation and expansion, known as vascular tumors. Treatment of this disease is quite challenging, but most children recover on their own.