Diabetic patients with gastric paresis on November 29, 2002

Diabetic patients with gastric paresis on November 29, 2002

Due to long-term stimulation from high blood sugar and ketones, diabetic patients experience autonomic nervous system dysfunction in the gastrointestinal tract, resulting in markedly reduced gastrointestinal motility and impaired gastric emptying—a condition clinically known as gastric paresis. In such cases, instead of the usual symptoms of polydipsia, polyphagia, and polyuria, the first symptoms are nausea, vomiting, and upper abdominal bloating. Recent research suggests that injecting botulinum toxin into the pylorus can treat this condition, possibly by inhibiting the release of acetylcholine in the pyloric region, thereby relaxing the pylorus and improving gastric emptying.