Cholestatic Jaundice in Infants Aged 2–8 Weeks, December 27, 2004

Cholestatic Jaundice in Infants Aged 2–8 Weeks, December 27, 2004

This type of jaundice is characterized by elevated conjugated bilirubin and occurs between 2 and 8 weeks of age, indicating dysfunction of the liver and biliary tract. Jaundice occurring within the first week is neonatal jaundice, characterized by unconjugated bilirubin; this type is physiological jaundice and milk-related jaundice. Cholestatic jaundice occurs in approximately 1 out of 2,500 cases, with the most common causes being bile duct atresia and neonatal hepatitis. Neonatal hepatitis refers to a diffuse cytomegalic transformation observed histologically, a nonspecific change not caused by HV but related to infection and metabolism.