New Understanding of Aspirin, October 15, 1996

New Understanding of Aspirin, October 15, 1996

1. When body tissues become inflamed or injured, the affected area releases prostaglandins, which can cause local vasodilation, inflammatory exudation, and polymorphonuclear infiltration. All these pathological reactions can further increase the release of prostaglandins. In addition, the increase in prostaglandins can also lead to two important pathological phenomena: ① Fever; ② Hyperalgesia. The fundamental reason for aspirin's antipyretic and analgesic effects is its ability to inhibit the production of prostaglandins, thereby addressing the aforementioned pathological reactions and eliminating the resulting pathological phenomena.

2. Aspirin can also inhibit platelet aggregation, thus treating thrombocytopenic purpura.

3. Aspirin has a clear preventive effect on myocardial infarction, opening up new avenues in the treatment of coronary heart disease.

4. Aspirin can also treat diabetic retinopathy, an effect that is also due to its inhibition of platelet aggregation. It is also suitable for blackouts caused by retinal artery thrombosis. Overall, aspirin has obvious efficacy against all thrombotic diseases, because it inhibits platelet aggregation. In summary, aspirin's effects can be categorized into two: ① Inhibiting prostaglandin production; ② Inhibiting platelet aggregation. The former creates aspirin's antipyretic and analgesic effects; the latter creates aspirin's anti-thrombotic and anti-infarction effects.