Research on Pei Zhengxue's Formulation Series

3.6 Effects of Pei’s Shengxue Granules Combined with 5-Fu on Serum IFN-γ Concentration in Tumor-Bearing Mice

Chapter 137

### 3.6 Effects of Pei’s Shengxue Granules Combined with 5-Fu on Serum IFN-γ Concentration in Tumor-Bearing Mice

From Research on Pei Zhengxue's Formulation Series · Read time 1 min · Updated March 22, 2026

Keywords方药研究, 实验研究, 配方资产, 转化沟通, 2 体会与展望

Section Index

  1. 3.6 Effects of Pei’s Shengxue Granules Combined with 5-Fu on Serum IFN-γ Concentration in Tumor-Bearing Mice

3.6 Effects of Pei’s Shengxue Granules Combined with 5-Fu on Serum IFN-γ Concentration in Tumor-Bearing Mice

As shown in Table 5, the serum IFN-γ concentration in the 5-Fu group was significantly lower, with statistically significant differences compared with the model group (P<0.05). In the Pei’s Shengxue Granules combined with 5-Fu groups, the serum IFN-γ concentration increased, with the high- and medium-dose groups showing particularly noticeable increases, and statistically significant differences compared with the 5-Fu group (P<0.05). See Table 5 and Figure 8 for details.

Table 5: Effects of Pei’s Shengxue Granules Combined with 5-Fu on Serum IFN-γ in Tumor-Bearing Mice (n=8, x̄±s)

GroupDosage (g·kg⁻¹)IFN-γ (ng·mL⁻¹)
Model Group54.4±9.3
5-Fu Group0.0240.6±7.2*
Low-Dose Pei’s Shengxue Granules + 5-Fu2.5+0.0246.5±10.0
Medium-Dose Pei’s Shengxue Granules + 5-Fu5.0+0.0256.9±14.5△
High-Dose Pei’s Shengxue Granules + 5-Fu10.0+0.0253.7±8.4△

(*P<0.05 compared with the model group, △P<0.05 compared with the 5-Fu group)

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