Keywords：方药研究, 实验研究, 配方资产, 转化沟通, 1 结论
Section Index
3.5 Effects of Pei’s Shengxue Granules Combined with 5-Fu on Serum TNF-α Concentration in Tumor-Bearing Mice
As shown in Table 4, the serum TNF-α concentration in the 5-Fu group was significantly lower, with statistically significant differences compared with the model group (P<0.05). In the Pei’s Shengxue Granules combined with 5-Fu groups, the serum TNF-α concentration increased, with the medium-dose group showing a particularly noticeable increase, and statistically significant differences compared with the 5-Fu group (P<0.05). See Table 4 and Figure 7 for details.
Table 4: Effects of Pei’s Shengxue Granules Combined with 5-Fu on TNF-α in Tumor-Bearing Mice (n=8, x̄±s)
| Group | Dosage (g·kg⁻¹) | TNF-α (ng·mL⁻¹) |
|---|---|---|
| Model Group | — | 0.69±0.12 |
| 5-Fu Group | 0.02 | 0.55±0.11* |
| Low-Dose Pei’s Shengxue Granules + 5-Fu | 2.5+0.02 | 0.62±0.15 |
| Medium-Dose Pei’s Shengxue Granules + 5-Fu | 5.0+0.02 | 0.71±0.18△ |
| High-Dose Pei’s Shengxue Granules + 5-Fu | 10.0+0.02 | 0.65±0.09 |
(*P<0.05 compared with the model group, △P<0.05 compared with the 5-Fu group)
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