2 Reflections and Prospects

2 Reflections and Prospects

Pei's Shengxue Granules are a formula for treating malignant tumors formulated by Professor Pei Zhengxue based on more than forty years of clinical experience. This formula integrates warming the kidneys, tonifying the spleen, replenishing qi, and nourishing blood, with the overarching principle of reinforcing vital energy and consolidating the root. Over the years, it has achieved relatively satisfactory clinical results in the treatment of malignant tumors, proving that Pei's Shengxue Granules are not only highly effective against leukemia but also demonstrate significant clinical efficacy against malignant tumors, especially those accompanied by weakened immune function caused by radiotherapy and chemotherapy. Recent animal experiments have shown that the effects of Pei's Shengxue Granules on malignant tumors are consistent with the clinical results obtained.

The basis for this research project comes from the inspiration drawn from Professor Pei Zhengxue's more than forty years of clinical experience, fully reflecting the idea that clinical experience guides experimental research and avoiding the blindness of experimental studies. This experiment explores the anti-tumor mechanism and the synergistic and detoxifying effects of Pei's Shengxue Granules at the molecular level, providing a scientific basis for the application of this drug in the treatment of malignant tumors and for its synergistic and detoxifying effects when used in conjunction with chemotherapy drugs, as well as a scientific and microscopic basis for the widespread clinical application of Pei's Shengxue Granules.

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Appendix 1: Expression of P27 Protein in Mouse H22 Liver Cancer Xenograft Tissue (SP Method)

• Model Group (Immunohistochemical Staining, ×400)
• 5-Fu Group (Immunohistochemical Staining, ×400)
• Low-Dose PG+5-Fu Group (Immunohistochemical Staining, ×400)
• Medium-Dose PG+5-Fu Group (Immunohistochemical Staining, ×400)
• High-Dose PG+5-Fu Group (Immunohistochemical Staining, ×400)

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Appendix 2: Flow Cytometry Diagrams of Tumor Cell Cycle and Apoptosis Rate in H22 Tumor-Bearing Mice

• Model Group
• 5-Fu Group
• Low-Dose PG+5-Fu Group
• Medium-Dose PG+5-Fu Group
• High-Dose PG+5-Fu Group

Research on Pei Zhengxue's Series of Formulas and Medicines