Keywords:方药研究, 实验研究, 配方资产, 转化沟通, 2.7.2 IFN-γ浓度测定
Section Index
1 Conclusion
1.1 Pei's Shengxue Granules can significantly inhibit the growth of H₂₂ tumors in tumor-bearing mice, slowing down the rate of tumor growth, demonstrating a remarkable anti-tumor pharmacological effect, consistent with the clinical efficacy achieved by Pei's Shengxue Granules over many years.
1.2 Pei's Shengxue Granules has a clear weight-increasing effect on the immune organs—the thymus and spleen—of tumor-bearing mice, thereby enhancing their non-specific immune function.
1.3 Pei's Shengxue Granules can significantly inhibit VEGF expression in tumor tissue of tumor-bearing mice and simultaneously increase the level of IL-12 in the serum. This suggests that the drug may achieve anti-tumor effects by downregulating VEGF expression in tumor tissue and upregulating IL-12 levels in the serum, thereby inhibiting tumor angiogenesis and preventing tumor growth and metastasis.
In conclusion, Pei's Shengxue Granules has a certain regulatory effect on the immune function of tumor-bearing mice. From a macro perspective, Pei's Shengxue Granules' anti-tumor effect is achieved through the overall effect of reinforcing righteous qi and consolidating the root, improving the abnormal state of immune suppression; from a micro perspective, molecular biological tests reveal that Pei's Shengxue Granules can regulate VEGF expression and IL-12 levels in tumor-bearing mice, inhibiting tumor angiogenesis and thus achieving anti-tumor effects, improving the quality of life of tumor-bearing mice, and receiving favorable evaluations for its efficacy.
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