4.1 Anti-Tumor Effect of Pei’s Soft Liver and Anti-Bloating Pill

4.1 Anti-Tumor Effect of Pei’s Soft Liver and Anti-Bloating Pill

Tumor experimental research is the most fundamental method and approach in oncology. Replicating human tumors in animal models—both in vivo and in vitro—known as tumor animal models, is an essential prerequisite for conducting tumor experiments. This experiment was conducted in an SPF-grade laboratory using the H₂₂ mouse xenograft tumor model, which is a typical in vivo experimental model for evaluating drug anti-tumor effects and regulating the body’s immunity. The modeling method involves transplanting H₂₂ tumor cells into mice and allowing them to continuously proliferate within the mice. The advantages of this model include a simple transplantation method that requires no special equipment, a high success rate, the ability to maintain the integrity of the organism, and the maintenance of normal contact between the organism and the external environment, thus providing a more objective reflection of the drug’s anti-tumor activity [17].

The results of this experiment show that the average tumor weight in the high-, medium-, and low-dose groups of Pei’s Soft Liver and Anti-Bloating Pill was lower than that of the Model Control Group, at (0.926±0.237) g, (0.776±0.122) g, and (0.935±0.227) g, respectively, all statistically significant compared with the Model Control Group (P<0.05). The corresponding anti-tumor rates were 24.5%, 36.8%, and 23.9%, indicating that Pei’s Soft Liver and Anti-Bloating Pill has a good effect in inhibiting tumor growth.