Research on Pei Zhengxue's Formulation Series

2.3.2 Activating Blood Circulation and Removing Blood Stasis Method

Chapter 238

### 2.3.2 Activating Blood Circulation and Removing Blood Stasis Method

From Research on Pei Zhengxue's Formulation Series · Read time 1 min · Updated March 22, 2026

Keywords方药研究, 实验研究, 配方资产, 转化沟通, 2.1 病名溯源

Section Index

  1. 2.3.2 Activating Blood Circulation and Removing Blood Stasis Method

2.3.2 Activating Blood Circulation and Removing Blood Stasis Method

Qingyun Pavilion, in “Excerpts from Medical Texts: Miscellaneous Treatments—Practical Cases,” analyzed: “Accumulations are caused by stagnation of qi and blood. Accumulations are essentially blood that has stagnated and cannot flow freely.” Meanwhile, “Compendium of Sacred Healing” states: “For lumps, masses, and accumulations… if qi and blood can circulate freely, the illness can be cured.” Building on these ancient insights, modern pharmacological research also shows that blood-activating and blood-stasis-removing prescriptions have a clear inhibitory effect on tumor metastasis [8]. For example, the Diaphragm Below Decoction has a notable inhibitory effect on H22 liver cancer-bearing mice, with its mechanism involving suppression of telomerase activity, thereby preventing unlimited DNA replication in cells, as well as upregulation of P53 and Bax and downregulation of Bcl-2 [9–11].

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