Keywords:方药研究, 实验研究, 配方资产, 转化沟通, 2.1 病名溯源
Section Index
2.3.2 Activating Blood Circulation and Removing Blood Stasis Method
Qingyun Pavilion, in “Excerpts from Medical Texts: Miscellaneous Treatments—Practical Cases,” analyzed: “Accumulations are caused by stagnation of qi and blood. Accumulations are essentially blood that has stagnated and cannot flow freely.” Meanwhile, “Compendium of Sacred Healing” states: “For lumps, masses, and accumulations… if qi and blood can circulate freely, the illness can be cured.” Building on these ancient insights, modern pharmacological research also shows that blood-activating and blood-stasis-removing prescriptions have a clear inhibitory effect on tumor metastasis [8]. For example, the Diaphragm Below Decoction has a notable inhibitory effect on H22 liver cancer-bearing mice, with its mechanism involving suppression of telomerase activity, thereby preventing unlimited DNA replication in cells, as well as upregulation of P53 and Bax and downregulation of Bcl-2 [9–11].
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