Keywords：方药研究, 实验研究, 配方资产, 转化沟通, 4.1 裴氏软肝消痞丸方药药理概括
Section Index
3.4 Effects of Pei's Soft Liver and Anti-Flatulence Pill on VEGF Expression in Mouse Tumor Tissue
In the model control group, large areas of brown-yellow granules were observed in the cytoplasm, indicating strong positive expression; in all treatment groups, the brown-yellow granules were fewer than in the model control group. The MOD was proportional to the positive expression, and the positive expression of VEGF in tumor tissues of the PRGXP low-, medium-, and high-dose groups as well as the cantharidin group was lower than that of the model group, with all differences being statistically significant (p<0.05). There was no statistically significant difference between the PRGXP low-, medium-, and high-dose groups and the cantharidin group (p>0.05). See Table 3 and Figure 5.
Table 3: Effects of Pei's Soft Liver and Anti-Flatulence Pill on VEGF Expression in H22 Mouse Tumor Tissue (x±S)
| Group | Number of Mice | Dose (g/kg) | VEGF MOD |
|---|---|---|---|
| Model Control Group | 8 | — | 0.364±0.007 |
| PRGXP low-dose group | 8 | 1.0 | 0.298±0.007* |
| PRGXP medium-dose group | 8 | 2.0 | 0.287±0.014* |
| PRGXP high-dose group | 8 | 4.0 | 0.300±0.008* |
| Cantharidin group | 8 | 0.25 | 0.295±0.018* |
Note: *p<0.05 compared with the model control group
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