Keywords：方药研究, 实验研究, 配方资产, 转化沟通, 1 裴氏"软肝消痞丸"配合西医治疗PLC的理论依据
Section Index
3.5 Effects of Pei’s Soft Liver and Anti-Bloating Pill on Bcl-2 Expression in Tumor Tissue of Tumor-Bearing Mice
There are fewer brown-yellow granules in the cytoplasm of cells in all treatment groups; the model control group shows large areas of brown-yellow granules in the cytoplasm, indicating strong positive expression. The MOD is proportional to the selected positive expression. The positive expression of Bcl-2 in the tumor tissues of the PRGXP small-, medium-, and large-dose groups as well as the BM group is all lower than that of the model group, and all comparisons with the model control group are statistically significant (p<0.05). The positive expression of Bcl-2 in the tumor tissues of the PRGXP medium-dose group is lower than that of the BM group, and this difference is statistically significant (p<0.05). (See Table 4, Figures 6, 12–16)
Table 4: Effects of Pei’s Soft Liver and Anti-Bloating Pill on Bcl-2 Expression in Tumor Tissue of Tumor-Bearing Mice (x̄±S)
| Group | Number of Mice | Dosage (g·kg⁻¹) | Bcl-2 MOD |
|---|---|---|---|
| Model Control Group | 8 | — | 0.361±0.015 |
| PRGXP Small-Dose Group | 8 | 1.0 | 0.299±0.016 |
| PRGXP Medium-Dose Group | 8 | 2.0 | 0.250±0.011 |
| PRGXP Large-Dose Group | 8 | 4.0 | 0.276±0.013 |
| BM Group | 8 | 0.25 | 0.300±0.008 |
Note: Compared with the model control group, p<0.05; compared with the BM group, p<0.05
Figure 6: Effects of Pei’s Soft Liver and Anti-Bloating Pill on Bcl-2 Expression in Tumor Tissue of Tumor-Bearing Mice
(Compared with the model control group, *p<0.05; compared with the BM group, p<0.05)
4 Discussion
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