Keywords：方药研究, 实验研究, 配方资产, 转化沟通, 裴氏软肝消痞丸配合西医治疗原发性肝癌的临床研究
Section Index
3.4 Effects of Pei’s Soft Liver and Anti-Bloating Pill on P27 Expression in Tumor Tissue of Tumor-Bearing Mice
Large areas of brown-yellow granules can be seen in the nuclei of cells in all treatment groups, indicating strong positive expression, significantly higher than that of the model control group. The average optical density (MOD) is proportional to the selected positive expression. The positive expression of P27 in the tumor tissues of the PRGXP small-, medium-, and large-dose groups as well as the BM group is all higher than that of the model control group, and all comparisons with the model control group are statistically significant (p<0.05). There is no statistically significant difference between the PRGXP small-, medium-, and large-dose groups and the BM group (p>0.05). (See Table 3, Figures 5, 7–11)
Table 3: Effects of Pei’s Soft Liver and Anti-Bloating Pill on P27 Expression in Tumor Tissue of Tumor-Bearing Mice (x̄±S)
| Group | Number of Mice | Dosage (g·kg⁻¹) | P27 MOD |
|---|---|---|---|
| Model Control Group | 8 | — | 0.263±0.012 |
| PRGXP Small-Dose Group | 8 | 1.0 | 0.305±0.013 |
| PRGXP Medium-Dose Group | 8 | 2.0 | 0.332±0.014 |
| PRGXP Large-Dose Group | 8 | 4.0 | 0.320±0.010 |
| BM Group | 8 | 0.25 | 0.310±0.016 |
Note: Compared with the model control group, p<0.05
Figure 5: Effects of Pei’s Soft Liver and Anti-Bloating Pill on P27 Expression in Tumor Tissue of Tumor-Bearing Mice
(Compared with the model control group, *p<0.05)
This chapter is prepared for online research and reading; for external materials, please align with original publications and the review process.