Hemolytic anemia HA on January 27, 2003

Hemolytic anemia (HA) on January 27, 2003

HA is generally divided into intravascular hemolysis and extravascular hemolysis, with causes further categorized as intracellular abnormalities and extracellular abnormalities. ① Intracellular abnormalities: hereditary spherocytosis, paroxysmal nocturnal hemoglobinuria, glucose-6-phosphate dehydrogenase deficiency. ② Extracellular abnormalities: β-lipoprotein deficiency (spiky cell syndrome), chemical substances, physical factors, and hemolysis caused by hyperfunction of the spleen. Characteristics of HA: ① Increased free hemoglobin (>4%); ② Increased serum iron >21 µmol/L; ③ Increased iron granulocytes in bone marrow (+ to +++); ④ Positive occult blood in hemoglobinuria; ⑤ Increased bilirubin; ⑥ Increased urobilinogen and urobilin; ⑦ Reticulocyte increase >1% to 3%, reaching up to 30% in severe cases. Single remedy for HA: 15 g of saltpeter, 30 g of black alum, 30 g of turmeric, 30 g of danshen, ground into powder, made into pills of 9 g, taken three times daily with yinchen water.