Collected Medical Papers of Pei Zhengxue, Volume 1

2 Heart Blood Deficiency, Heart Yin Deficiency, and Death of Yin

Chapter 3

Palpitations, shortness of breath, and a thin or irregular pulse are the basic symptoms of Heart Qi Deficiency. If accompanied by feeling cold and sweating, it indicates Heart Yang Deficiency; if Heart Yang Deficiency fu

From Collected Medical Papers of Pei Zhengxue, Volume 1 · Read time 5 min · Updated March 22, 2026

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Palpitations, shortness of breath, and a thin or irregular pulse are the basic symptoms of Heart Qi Deficiency. If accompanied by feeling cold and sweating, it indicates Heart Yang Deficiency; if Heart Yang Deficiency further progresses, facial pallor, cold sweat, cold limbs, and a nearly absent pulse may occur, indicating Death of Yang. Heart Qi Deficiency, Heart Yang Deficiency, and Death of Yang are three progressively deepening pathological stages. Extreme Qi deficiency leads to extreme Yang deficiency, and extreme Yang deficiency leads to Death of Yang—this is one of the fundamental concepts of Traditional Chinese Medicine pathology. For Heart Qi Deficiency and Heart Yang Deficiency, it is advisable to tonify Qi and calm the heart, using Yang Xin Tang (formulated by Wang Kentang); for Death of Yang, it is recommended to restore Yang and save the situation, using Shen Fu Tang (formulated by Wei Yilin) or Si Ni Tang (formulated by Zhang Zhongjing).

  1. Heart Blood Deficiency, Heart Yin Deficiency, and Death of Yin

Palpitations, forgetfulness, insomnia, and excessive dreaming are the basic symptoms of Heart Blood Deficiency. If accompanied by tidal fever, bone-steaming, five-heart vexation, and night sweats, it indicates Heart Yin Deficiency; if Heart Yin Deficiency further progresses, symptoms such as restlessness, difficulty breathing, and warm hands and feet may appear, indicating Death of Yin. Heart Blood Deficiency, Heart Yin Deficiency, and Death of Yin are three progressively deepening pathological stages. Extreme blood deficiency leads to extreme Yin deficiency, and extreme Yin deficiency leads to Death of Yin—this is another fundamental concept of TCM pathology. For Heart Blood Deficiency and Heart Yin Deficiency, it is advisable to nourish blood and calm the spirit, using Tian Wang Bu Xin Dan (formulated by Wei Yilin); for Death of Yin, it is recommended to tonify Qi and nourish Yin, using Sheng Mai San (formulated by Sun Simiao).

  1. Excessive Heart Fire

Restless chest, insomnia, red tip of the tongue, and thin, rapid pulse are the basic symptoms of Excessive Heart Fire. If accompanied by oral and lingual erosion and reddish, stinging urine, it indicates that Heart Fire has transferred its heat to the Small Intestine (organ heat transferring to腑). The source of Heart Fire lies in the chest; when it becomes excessive, its upward-inflaming tendency is even stronger, and the basic symptom clusters are all rooted in this principle. The Heart and Small Intestine are mutually connected through meridians, so although the fire rises, it can also descend along the meridians into the Small Intestine. "The Small Intestine is the organ responsible for receiving and transforming substances, and it plays a role in separating the pure from the impure." When the Small Intestine is hot, the urine becomes reddish and stinging. Oral and lingual erosion occurs because the Small Intestine's dampness is carried upward by the fiery nature. For Excessive Heart Fire, it is advisable to drain fire and calm the spirit, using Huang Lian A Jiao Tang (formulated by Zhang Zhongjing); for Heart Fire transferring heat to the Small Intestine, it is recommended to guide the heat downward, using Dao Chi San (formulated by Qian Yi).

  1. Phlegm Obscuring the Heart Orifice

Confusion of consciousness (restlessness, mania, laughter, speech), slippery pulse, and greasy tongue are the basic symptoms of this syndrome. It is advisable to resolve phlegm, open the heart orifice, and calm the spirit, using Sheng Tie Luo Yin (formulated by Cheng Zhongling). The Heart governs the spirit, and when the heart orifice is blocked, consciousness becomes confused; the slippery pulse and greasy tongue are manifestations of phlegm, indicating that the blockage of the heart orifice is caused by phlegm.

  1. Heart Blood Stasis

Pain in the precordial region, radiating pain to the arm, palpitations and shortness of breath, purple-dark tongue, and a sluggish, irregular pulse are the basic symptoms of this syndrome. It is advisable to activate blood circulation, remove stasis, and promote the flow of yang, using Guan Xin II (a collaborative group in Beijing) or Gua Wei Xie Bai Ban Xia Tang (formulated by Zhang Zhongjing): a sluggish pulse and a purple-dark tongue indicate blood stasis; precordial pain and palpitations indicate that the site of blood stasis is in the heart.

3. Liver Disease Differentiation:

  1. Liver Qi Stagnation

Bitter taste in the mouth, dry throat, irritability, fullness and distension in the chest and hypochondrium, and a taut pulse are the basic symptoms of this syndrome. If accompanied by abdominal distension, loss of appetite, and regurgitation, it is considered Liver-Stomach Disharmony; if accompanied by a sensation of something stuck in the throat that cannot be swallowed or expelled, it is considered Liver Qi Reversal (Mei Ke Qi). For Liver Qi Stagnation, it is advisable to soothe the liver and relieve stagnation, using Chai Hu Shu Gan San (formulated by Zhang Jingyue); for Liver-Stomach Disharmony, it is advisable to soothe the liver and harmonize the stomach, using Xiao Yao San (as recorded in the "Jufang"); for Liver Qi Reversal, it is advisable to soothe the liver and lower the qi, using Ban Xia Hou Pu Tang (formulated by Zhang Zhongjing). The liver is naturally inclined to flow freely; when it becomes stagnant, it rebels against the stomach (Liver-Stomach Disharmony) as the first manifestation; when it becomes rebellious, it rushes upward toward the throat (Mei Ke Qi) as the second manifestation. Both are products of Liver Qi Stagnation.

  1. Liver-Gallbladder Exuberant Fire

Bitter taste in the mouth, dry throat, irritability, fullness and distension in the chest and hypochondrium, dizziness, headache, tinnitus, red face and eyes, palpitations and rapid breathing, short and reddish urine, and a taut, rapid pulse—all indicate the need to clear liver fire, using Long Dan Xie Gan Tang (as recorded in the "Yizong Jin Jian"). This syndrome often arises from prolonged stagnation turning into fire, so the basic symptom clusters consist of two parts: ① bitter taste in the mouth, dry throat, irritability, and fullness in the chest and hypochondrium (Liver Qi Stagnation). ② dizziness, headache, red face and eyes, short and reddish urine, and a rapid pulse (fire inflaming upward). Palpitations and rapid breathing, along with tinnitus and dizziness, are manifestations of the dominant fire.

'3) Liver Yin Deficiency

Dizziness, lumbago, tinnitus, bone-steaming tidal fever, five-heart vexation, night sweats, numbness and tremors in the hands and feet, red tongue with little coating, a thin and rapid pulse—all indicate the need to nourish water and sustain wood, using Qi Ju Di Huang Wan. The liver and kidneys share the same origin, and the liver relies on kidney Yin to nourish itself; therefore, the manifestations of Liver Yin Deficiency consist of three parts: ① dizziness and lumbago, along with tinnitus (kidney deficiency symptoms). ② bone-steaming tidal fever, five-heart vexation, and night sweats (yin deficiency symptoms). ③ numbness and tremors in the hands and feet (yin failing to nourish the tendons).

  1. Internal Liver Wind Movement (All wind-related dizziness belongs to the Liver) ① Extreme Heat Generates Wind (Wind and Fire Fan Each Other) High fever, palpitations, convulsions, syncope, and a taut, rapid pulse—all indicate the need to clear fire and calm the mind, using Ling Yang Gou Teng Tang (formulated by Yu Gen Chu). ② Excessive Yang Generates Wind (All Violent Rigidity Belongs to Wind)

Severe headache, hemiplegia with aphasia, facial and ocular deviation, convulsions, and coma—all indicate the need to calm the liver and extinguish wind, using Zhen Gan Xi Feng Tang (formulated by Zhang Xichun).

③ Blood Deficiency Generates Wind (Blood Fails to Nourish the Tendons) Tremors, numbness, and convulsions—all indicate the need to nourish blood and extinguish wind, using Da Ding Feng Zhu (as recorded in the "Wen Bing Tiao Bian"). 5) Cold Stagnation in the Liver Meridian Lower abdominal pain, contraction of the scrotum, and heavy testicular descent—all indicate the need to warm the liver and dispel cold, using Nuan Gan Jian (formulated by Zhang Jingyue). The lower abdomen, scrotum, and testicles are all areas traversed by the Foot-Yin Liver Meridian. 4. Lung Disease Differentiation:

  1. Lung Cold Cough

Headache, fever, chills, cough, thin and clear sputum, and a floating, tight pulse—all indicate the need to disperse exterior cold, clear heat, and stop coughing, using Ma Huang Tang (formulated by Zhang Zhongjing). This syndrome is a combination of wind-cold exterior syndrome and cough.

  1. Lung Heat Cough

Headache, fever, thirst, increased drinking, irritability, coughing and wheezing, red tongue, and a rapid pulse—all indicate the need to clear heat, open the lungs, and stop coughing, using Ma Xing Shi Gan Tang (formulated by Zhang Zhongjing). This syndrome is a combination of wind-heat exterior syndrome and cough.

  1. Lung Dryness Cough

Dry mouth, dry throat, dry nose, cough with sticky sputum, and a tongue with little moisture—all indicate the need to clear dryness and rescue the lungs, using Qing Zao Jiu Fei Tang (formulated by Yu Jiayan). Dryness manifests in three forms, and this syndrome is a combination of the three dryness symptoms and sticky cough.

  1. Phlegm Turbidity Blocking the Lungs

Sticky sputum obstructing the airways, coughing and gasping to the point of being unable to lie down—all indicate the need to guide phlegm and open the lungs, using Su Zi Jiang Qi Tang (as recorded in the "Jufang") or Ting Li Da Zao Xie Fei Tang (formulated by Zhang Zhongjing).

:5') Lung Qi Deficiency:

Pale complexion, shortness of breath, fatigue, coughing and sputum, a thick and pale tongue, a moist and thin pulse—all indicate the need to tonify lung qi, using Bu Fei Tang with added ingredients (an empirical formula).

  1. Lung Yin Deficiency

Coughing and sputum, thin and sticky sputum, blood in the sputum, bone-steaming tidal fever, five-heart vexation, and night sweats—all indicate the need to nourish yin and clear the lungs, using Bai He Gu Jin Tang (formulated by Zhao E'an). This syndrome consists of yin-deficiency symptoms and lung-cough symptoms.

5. Kidney Disease Differentiation:

Dizziness, tinnitus, lumbago, leg fatigue, and a weak pulse at the cun position—are the basic symptoms of kidney deficiency. If accompanied by bone-steaming, tidal fever, five-heart vexation, and night sweats, it indicates kidney Yin deficiency; if accompanied by feeling cold and sweating, it indicates kidney Yang deficiency. For kidney Yin deficiency, it is advisable to nourish yin and tonify the kidneys, using Liu Wei Di Huang Tang (formulated by Qian Zhongyang); kidney Yang deficiency can be further divided into four types, each treated separately.

  1. Kidney Does Not Store Essence: For basic symptoms of kidney Yang deficiency accompanied by nocturnal emission and erectile dysfunction, it is advisable to strengthen the kidneys and solidify essence, using Bu Shen Wan (an empirical formula).

  2. Kidney Does Not Take in Qi: For basic symptoms of kidney Yang deficiency accompanied by shortness of breath and wheezing, it is advisable to warm the kidneys and help them take in qi, using Du Qi Wan (as recorded in the "Yizong Yi Ren Bian").

  3. Decline of Life Gate Fire: For basic symptoms of kidney Yang deficiency accompanied by diarrhea at dawn, it is advisable to warm the kidneys and stop diarrhea, using Si Shen Wan (as recorded in the "Neike Zhai Yao").

  4. Yang Deficiency Leading to Water Overflow: For basic symptoms of kidney Yang deficiency accompanied by generalized edema, it is advisable to warm the yang and transform the water, using Zhen Wu Tang (formulated by Zhang Zhongjing). Appendix: 1) Lower Yuan Deficiency and Cold: Night urination, enuresis, frequent urination, and cold lower abdomen—all indicate the need to warm and tonify the lower yuan, using Suo Quan Wan (as recorded in the "Furen Liang Fang").

  5. Bladder Damp-Heat: Urgent urination, frequent urination, painful urination, and acute lower abdominal discomfort—all indicate the need to clear heat, eliminate dampness, and facilitate urination, using Ba Zheng San (as recorded in the "Jufang").

The aforementioned Zang-Fu syndromes may appear individually in clinical practice, but in most cases, several Zang-Fu syndromes occur in combination. For example, Heart-Spleen Dual Deficiency Syndrome, Spleen-Kidney Yang Deficiency Syndrome, and Liver-Kidney Yin Deficiency Syndrome. Heart-Spleen Dual Deficiency Syndrome is a combination of Heart Blood Deficiency and Spleen Qi Deficiency, meaning it includes both the pale complexion, poor appetite, fatigue, and shortness of breath associated with Spleen Qi Deficiency, as well as the palpitations, forgetfulness, insomnia, and excessive dreaming associated with Heart Blood Deficiency. The treatment formula for this syndrome is Gui Pi Tang, which contains both herbs that tonify the Spleen, such as Dang Shen, Bai Zhu, and Huang Qi, and herbs that tonify the Heart, such as Yuan Zhi and Zao Ren. As long as one understands the individual Zang-Fu syndromes, it is relatively easy to analyze and understand their combined clinical manifestations. III. Progress in Integrating Zang-Fu Differentiation with Western Medicine 1. Immunological Aspects: In recent years, numerous domestic experimental studies have suggested that strengthening the Spleen and tonifying the Kidneys can improve the body's immune function. Specifically, strengthening the Spleen tends to enhance non-specific immune function, while tonifying the Kidneys focuses on improving specific immune function. Non-specific immunity refers to defense mechanisms that lack selectivity, such as the skin and mucosal barrier, the blood-brain barrier, the blood-fetal barrier, the reticuloendothelial system, and the phagocytic activity of neutrophils. Specific immunity, on the other hand, is highly targeted and only acts against corresponding pathogens; its function is carried out by immune-active T cells and antibodies present in body fluids that correspond to antigens.

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