Keywords：方药研究, 实验研究, 配方资产, 转化沟通, 3.5 裴氏升血颗粒联合5-Fu对荷瘤小鼠血清TNF-α浓度的影响
Section Index
3.3 Antitumor Effects of PG
The average tumor inhibition rates in the large-, medium-, and small-dose PG treatment groups as well as the Zhenqi control group differed significantly from those of the model group (p<0.05). Among them, the medium-dose PG treatment group achieved a tumor inhibition rate of 45.91%, demonstrating a clear antitumor effect. Specific results are detailed in Table 2 and Figure 2.
Table 2: Effects of Pei’s Shengxue Granules on Solid Tumor Inhibition Rate in Tumor-Bearing Mice (%; x̄±s)
| Group | Dose (g·kg⁻¹) | Number of Cases | Tumor Weight (x̄±s) | Tumor Inhibition Rate (%) |
|---|---|---|---|---|
| Model Control Group | — | 11 | 1.938±0.326 | — |
| PG Small-Dose Group | 2.5 | 11 | 1.375±0.284* | 29.18 |
| PG Medium-Dose Group | 5.0 | 12 | 1.052±0.173** | 45.91 |
| PG Large-Dose Group | 10.0 | 11 | 1.214±0.265* | 37.35 |
| Zhenqi Fuzheng Granules Control Group | 1.67 | 12 | 1.091±0.183** | 42.41 |
Note: Compared with the model group, **p<0.01, *p<0.05
Research on Pei Zhengxue Series Formulas
Review
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