Results

Results

1. Tumor Inhibition Effect: The tumor weights in the high-, medium-, and low-dose PG + 5-Fu groups were all lower than those in the 5-Fu group, with the medium-dose PG group showing the most significant inhibition rate of 61.7%, a highly significant difference (P<0.05).

2. Peripheral Blood Counts: The WBC and PLT counts in the high- and medium-dose PG + 5-Fu groups were significantly higher than those in the 5-Fu group (P<0.05).

3. Bone Marrow DNA Content: The bone marrow DNA content in the high-, medium-, and low-dose PG + 5-Fu groups was all higher than that in the 5-Fu group, with the high- and medium-dose groups showing particularly significant differences (P<0.05).

4. Serum TNF-α Concentration: The serum TNF-α concentrations in the high-, medium-, and low-dose PG + 5-Fu groups were all higher than those in the 5-Fu group, with the high-dose PG group reaching 0.71 ng·mL⁻¹, a highly significant difference compared to the 5-Fu group (P<0.05).

5. Serum IFN-γ Concentration: The serum IFN-γ concentrations in the high-, medium-, and low-dose PG + 5-Fu groups were all significantly higher than those in the 5-Fu group, with the high- and medium-dose groups showing particularly significant differences (P<0.05), at 53.7 pg·mL⁻¹ and 56.9 pg·mL⁻¹ respectively.