Keywords：方药研究, 实验研究, 配方资产, 转化沟通, 3.2 白介素-1（IL-1）的影响
Section Index
3.2 Effects of Pei's Hematopoietic Granules on Tumor Weight and Tumor Inhibition Rate in Tumor-Bearing Mice
The inhibitory effect of Pei's Hematopoietic Granules on tumors in tumor-bearing mice is manifested as follows: Different doses of Pei's Hematopoietic Granules all significantly inhibit tumor weight in tumor-bearing mice, with significant differences in average tumor weight compared with the model group (P<0.01). There are significant differences in average tumor weight between the high-, medium-, and low-dose Pei's Hematopoietic Granules groups and the low-dose group (P<0.05 or P<0.01). However, there is no significant difference in average tumor weight between the high-, medium-, and low-dose Pei's Hematopoietic Granules groups and the Zhenqi Fuzheng Granules group (P>0.05). The tumor inhibition rates for the high-, medium-, and low-dose Pei's Hematopoietic Granules groups and the Zhenqi Fuzheng Granules group are 36.26%, 37.56%, 24.91%, and 35.60%, respectively. (See Table 1, Figure 1, and Figure 2)
Table 1: Effects of Pei's Hematopoietic Granules on Tumor Weight and Tumor Inhibition Rate in Tumor-Bearing Mice (g; %; n=10; x̄±s)
| Group | Dosage (g/kg) | Tumor Weight (g, x̄±s) | Tumor Inhibition Rate (%) |
|---|---|---|---|
| Model Group | — | 2.601±0.378 | — |
| PG Low-Dose Group | 3.0 | 1.953±0.193 | 24.91 |
| PG中剂量组 | 6.0 | 1.624±0.079* | 37.56 |
| PG高剂量组 | 12.0 | 1.658±0.117 | 36.26 |
| ZG组 | 5.0 | 1.675±0.101 | 35.60 |
Note: Compared with the model group, △P<0.01; compared with the low-dose group, ▽P<0.05, *P<0.01
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