Keywords：方药研究, 实验研究, 配方资产, 转化沟通, 1 结论
Section Index
3.2 Effects of Pei’s Soft Liver and Anti-Bloating Pill on Tumor Weight and Tumor Inhibition Rate in Tumor-Bearing Mice
The average tumor weights of the PRGXP small-, medium-, and large-dose groups as well as the BM group are all lower than that of the model control group, at (0.935±0.227) g, (0.776±0.122) g, (0.926±0.237) g, and (0.925±0.320) g, respectively, all of which are statistically significant compared with the model control group (p<0.05); the tumor inhibition rates of the PRGXP small-, medium-, and large-dose groups are 23.9%, 36.8%, and 24.5%, respectively, while the BM group’s tumor inhibition rate is 24.6%. The tumor inhibition rate of the PRGXP medium-dose group is significantly higher than that of the cantharidin group and the PRGXP small- and large-dose groups. (See Table 1, Figures 1 and 2)
Table 1: Effects of Pei’s Soft Liver and Anti-Bloating Pill on Tumor Weight in Tumor-Bearing Mice (x±s)
| Group | Dosage (g·kg⁻¹) | Number of Mice | Average Tumor Weight (g) | Tumor Inhibition Rate (%) |
|---|---|---|---|---|
| Model Control Group | — | 12 | 1.227±0.193 | — |
| PRGXP Small-Dose Group | 1.0 | 12 | 0.935±0.227 | 23.9 |
| PRGXP Medium-Dose Group | 2.0 | 12 | 0.776±0.122 | 36.8 |
| PRGXP Large-Dose Group | 4.0 | 12 | 0.926±0.237 | 24.5 |
| BM Group | 0.25 | 12 | 0.925±0.320 | 24.6 |
Note: Compared with the model control group, p<0.05
Research on Pei Zhengxue’s series of prescriptions
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