2.1.1.3 Diagnostic criteria for the blast crisis phase BP

2.1.1.3 Diagnostic criteria for the blast crisis phase (BP)

2.1.1.3.1 Blast cells (type I + type II) or prolymphocytes + young lymphocytes or promonocytes + young monocytes exceeding 20% in the bone marrow; 2.1.1.3.2 Blast cells + early blast cells exceeding 30% in peripheral blood; 2.1.1.3.3 Blast cells + early blast cells exceeding 50% in the bone marrow; 2.1.1.3.4 Extramedullary infiltration occurs; 2.1.1.3.5 CFU-GM culture shows small clusters or no growth.[1]

Exclusion criteria:

First, exclude patients with other hematological diseases or malignancies. Second, exclude patients whose chronic myeloid leukemia has already transformed into acute leukemia. Third, exclude patients with severe concurrent diseases of the respiratory, circulatory, or urinary systems. Fourth, exclude patients whose treatment regimens are not standardized, making it impossible to assess efficacy.