Table of Contents
- Chinese Abstract
**Objective:** This experiment aims to verify the exact therapeutic effect of Pei’s Blood-Boosting Granules (PSSX) on immune-mediated aplastic anemia model mice by observing its impact on peripheral blood parameters, bon
- 1 Current Status of Domestic and International Research on Aplastic Anemia
### 1 Current Status of Domestic and International Research on Aplastic Anemia
- 1.1.2.2 Chronic Type
Characterized by a slower onset and progression, with milder symptoms compared to the acute type.
- 1.1.3 Diagnostic Criteria
The final revisions made at the Fourth Academic Conference on Aplastic Anemia in 1987 are as follows 1:
- 1.1.4 Differential Diagnosis
Aplastic anemia must be differentiated from the following diseases:
- 1.1.5 Main Treatments for Aplastic Anemia
Medications such as Kanglilong, Kangfuilong (oxymetholone), testosterone enanthate, compound long-acting testosterone injection (Qiaolibao, triolandren), and 17α-methyltestosterone (methandienonum, trade name Dianabol) a
- 1.1.5.1.4 Immunosuppressants
First, antilymphocyte globulin (ALG) and antithymocyte globulin (ATG): These agents kill suppressive T cells (Ts), CD8⁺ cells, and restore the normal CD4⁺/CD8⁺ ratio, while also possessing mitogenic effects that promote
- 1.1.5.1.5 Growth Factors
These can promote blood cell generation and are products of genetic engineering, such as recombinant granulocyte–macrophage colony-stimulating factor (rGM-CSF) and recombinant human granulocyte colony-stimulating factor
- 1.1.5.1.6 Lithium Carbonate
In vitro experiments have demonstrated that lithium salts stimulate the colony growth of human granulocytes, suggesting potential efficacy in treating aplastic anemia.
- 1.1.5.2 Transplantation Therapy
#### 1.1.5.2.1 Bone Marrow Transplantation (BMT)
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